http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5718664-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be3928f66bb2545a8175c61c56146b9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18a7d1606da2ec2ad08ae63822efb00e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-76 |
| filingDate | 1980-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b79be6b606a70f15fcbaa8b2acf9639 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_879ed816e5e92a1f747b319082f3ca2d |
| publicationDate | 1982-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5718664-A |
| titleOfInvention | N-substituted-bicyclo- 2.2.1 -hept-5-ene-2,3-dicarboximide derivative |
| abstract | NEW MATERIAL:An N-substituted-bicyclo-[2.2.1]-hept-5-ene-2,3-dicarboximide derivative expressed by formula I (n is 4W6; the bond between the 5- and the 6- positions represents a double bond). n EXAMPLE: N-(1-Hydroxycyclopentylmethyl)-bicyclo-[2.2.1]-hept-5-ene-2,3-dicarboximide. n USE: A remedy for cholecystitis, cholangitis, cholecystolithiasis and bile duct dyskinesia having improved cholagogic action. n PROCESS: A bicyclo-[2.2.1]-hept-5-ene-2,3-dicarboxylic anhydride expressed by formula II is refluxed with 1-aminomethylcyclopentanol hydrochloride, etc. in the presence of an organic base, e.g. triethylamine, in an organic solvent for several hours under heating to give the compound expressed by formula I in which the bond between the 5- and the 6- positions is a double bond. The resultant compound is then reduced in the presence of a catalyst, e.g. Raney nickel, to afford the compound expressed by formula I in which the bond between the 5- and the 6- positions is a single bond. n COPYRIGHT: (C)1982,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4743805-A |
| priorityDate | 1980-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.