abstract |
NEW MATERIAL:A compound of formula 1 (R 1 is lower alkyl, aralkyl, etc.; R 2 is lower alkyl, aralkyl, phenyl, etc.; X is methylene or vinylene; Y is O or s, except when both R 1 and R 2 are lower alkyl). n EXAMPLE: 3-Methyl-2-phenylcarbamoyliminothiazolidine. n USE: An anti-inflammatory agent and analgesic agent. n PROCESS: A compound of formula 2 is reacted with a compound of formula 3 to give the compound of formula 1. The reaction is carried out preferably in a solvent, e.g. ether, or under solventless conditions at -20°CW at a refluxing temperature of the solvent. The ratio between the compounds of formulas 2 and 3 is preferably usually about equimolar. n COPYRIGHT: (C)1982,JPO&Japio |