http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S57144255-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9822bceff022feda91b10019125e70f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-337 |
| filingDate | 1981-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1872e811b79127dfad38f3261828c6bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3de3868f678269b7240b50eeced11f76 |
| publicationDate | 1982-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S57144255-A |
| titleOfInvention | Alpha-methylthio(1-alkyl-2-pyrrolyl)acetamide derivative |
| abstract | NEW MATERIAL:The α-methylthio(1-alkyl-2-pyrrolyl)acetamide derivative of formulaI(R is lower alkyl; Y is H or methylthio; R 1 and R 2 are methyl or together with N atom form a ring). n EXAMPLE: N,N-Dimethyl-α-methylthio(1-methyl-2-pyrrolyl)acetamide. n USE: Raw material of tolmetin useful as an antiphlogistic agent and analgesic agent. n PROCESS: The compound of formulaIwherein Y is methylthio can be prepared e.g. by (1) reacting the 1-alkylpyrrole with the acid chloride of formula III, and (2) reacting the resultant (1-alkyl-2-pyrrolyl)glyoxylic acid amide derivative of formula IV with emthanethiol or its active derivative in the presence of a Lewis acid catalyst. The product can be converted to another compound of formulaIwherein Y is H by the reducive desulfurization. n COPYRIGHT: (C)1982,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11065228-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10201524-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9452168-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10596150-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10973821-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8993574-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012077221-A1 |
| priorityDate | 1981-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.