http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S57142966-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9822bceff022feda91b10019125e70f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-337 |
| filingDate | 1981-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3de3868f678269b7240b50eeced11f76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1872e811b79127dfad38f3261828c6bf |
| publicationDate | 1982-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S57142966-A |
| titleOfInvention | (1-alkyl-2-pyrrolyl)glyoxylic acid amide derivative |
| abstract | NEW MATERIAL:The (1-alkyl-2-pyrrolyl)glyoxylic acid amide derivative of formulaI(R is lower alkyl; R 1 and R 2 are methyl or together form a ring). n EXAMPLE: (1-Methyl-2-pyrrolyl)glyoxylic acid dimethyl amide. n USE: Raw materials for the preparation of tolmetin[(1-methyl-5-toluoyl-2-pyrrolyl) acetic acid]useful as a drug having antiphlogistic and analgesic activity. n PROCESS: The compound of formulaIcan be prepared by reacting aluminum chloride or aluminum bromide with nearly equimolar amount of the oxalic acid derivative of formula II in an inert solvent such as 1,2-dichloroethane at -20°CWroom temperature to activate the compound of formula II, and then reacting the activated compound with an 1-alkylpyrrole dissolved in the above inert solvent at -20W0°C. n COPYRIGHT: (C)1982,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10201524-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10973821-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9452168-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11065228-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8993574-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10596150-B2 |
| priorityDate | 1981-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.