http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S57140795-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_204ea9f0f83d1c51a916e46a41a6a14a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
| filingDate | 1981-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92b5dbdbb2968008aeb158620c8ee760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b4ecf8fe87f9db65cde68d2b1fef55c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce03f3e4c316a7c744a4d6552acd3a2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc3ff885db1cd16733d1765fcb73eb2a |
| publicationDate | 1982-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S57140795-A |
| titleOfInvention | Novel tylosin derivative |
| abstract | NEW MATERIAL:The compound of formulaI[R 1 is (lower alkyl-substituted) tetrahydrothiofuranyloxy or tetrahydrothiopyranyloxy; R 2 and R 3 are OH or alkanoyloxy; R 4 is H, OH or alkanoyloxy]. n EXAMPLE: 23-O-Tetrahydrothiofuranyl mycaminosyl tylonolide of formula II. n USE: Antibacterial agent. n PROCESS: For example, the compound of formula III (R' 3 is alkanoyloxy; R' 4 is H or alkanoyloxy) is made to reat with the compound of formula R 1 -CO-R (R is phenyl, diphenylacetyl or aralkyl) in an organic solvent such as methylene chloride in the presence of a mineral acid or an organic strong acid to afford the compound of formula IV having a tetrahydrothiofuranyloxy group or tetrahydrothiopyranyloxy group introduced to the 23-position. The compound can be converted to the compound of formula V (R' 4 is H or OH) by the dealkanoylation in an alcohol. n COPYRIGHT: (C)1982,JPO&Japio |
| priorityDate | 1981-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.