| abstract |
PURPOSE: An antiallergic agent containing an N 6 -ω-aminoalkyladenosine compound as an active constituent, having the antiallergic action, and useful as a remedy and a preventing agent for allerigic asthma, hay asthma, allergic colitis, etc. with slight side effects. n CONSTITUTION: An antiallergic agent containing an N 6 -ω-aminoalkyladenosine compound of formulaI(n is an integer 1W20; R is ribofuranosyl group of formula II, 5-phosphorylbribofuranosyl group of formula III, 3-phosphorylribofuranosyl group of formula IV or 3,5-cyclic phosphorylribofuranosyl group of formula V) or a salt thereof as an active constituent. The agent is prepared as a suspension, aerosol, absorbent, powder, etc. by the conventional method. The agent is administered by the internal use, inhalation, external use, etc. suitably, and the daily dose thereof is usually about 0.1W100mg per kg body weight. The compound of formulaIis obtained by reacting a compound of formula VI (X is halogen) with a compound of formula VII. n COPYRIGHT: (C)1982,JPO&Japio |