http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S57139096-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cfc033f059d282fcd915bc8be2ae53f |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate | 1981-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5c5bc65959c997b9774032c1bc1726f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3164963e9c3b20a786709ca0137c68b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_424964072c3005cb5d7023e47e083996 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85f362dbbe846741f825e533618acf9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32d60e61126fd664a2de12c72623334e |
| publicationDate | 1982-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S57139096-A |
| titleOfInvention | Heat denaturing deoxyribonucleic acid md-011 having antitumor activity and antitumor agent |
| abstract | NEW MATERIAL:A heat denaturing deoxyribonucleic acid MD-011. Elementary analysis %: C, 25.57-29.75; H, 3.80-4.75; N, 12.67-13.47; P, 7.30-7.91; Na, 8.12-11.59. Molecular weight: 30,000-1,000,000. Soluble in water and insoluble in ethanol, ether, acetone, etc. Negative to the orcinol, ninhydrin and anthrone reactions, and positive to the diphenylamine reaction. pH of the aqueous solution: 6.5-7.5. While powder. Base composition %: Guanine, 30.4; adenine, 16.9; cytosine, 30.8; thymine, 21.9. Loses the antitumor activity with deoxyribonuclease I, and no change with ribonuclease T2. Melting point and transition temperature: Indefinite. USE:An antitumor agent. PROCESS:A bacterium, e.g. bovine tubercle bacillus (ATCC19015), of the genus Mycobacterium is crushed and centrifuged to give an extract. A nucleic acid fraction of the resultant extract is then heat-treated. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2547500-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5855499-A |
| priorityDate | 1981-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.