| abstract |
NEW MATERIAL:A protein AN-3 having the follwing properties. Molecular weight: 13×10 3 (the gel filtration method). White. Positive to the ninhydrin and biuret reactions, and negative to the anthrone and Blix method. Solubility: soluble in water, and insoluble in methanol, acetone, propanol, etc. Elementary analysis %: N, 9.91; C, 36.66; H, 5.56; S, undetermined. Amino acid composition: 18 types such as lysine, threonine, glutamic acid, glycine, leucine, serine, alanine, etc. n USE: An antitumor agent. n PROCESS: A microorganism, e.g. Streptomyces albus (FERM-P No.5858), of the genus Streptomyces is cultivated at a pH of 4W9 and 25W38°C preferably under aerobic conditions. n COPYRIGHT: (C)1982,JPO&Japio |