http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S57123157-A

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filingDate 1981-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4823dc0d1809a88f1e1b1835651d596e
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publicationDate 1982-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S57123157-A
titleOfInvention Indane derivative and its preparation
abstract NEW MATERIAL:A compound shown by the formula I(R 1 is H, lower alkyl, aralkyl; R 2 is H or lower alkyl; R 3 is aralkyl; R 4 is H or acyl derived from a carboxylic acid) or its salt. n EXAMPLE: N-(5-Benzamido-4-oxo-6-phenylhexanoyl)-N-(2-indanyl)glycine. n USE: Having inhibiting actions on an enzyme capable of converting angiotension or of decomposing bradykinin, a diagnosticum, preventive or remedy for hypertension, anodyme, and enhancer for analgesic action. n PROCESS: A compound shown by the formula II is reacted with a compound shown by the formula III or its reactive derivative at its carboxyl in a proper solvent at -20W150°C, to give a compound shown by the formula I. The compound shown by the formula II as the starting material is obtained by condensing 2-indanone with a compound shown by the formula IV or under reducing conditions in an organic solvent preferably at -20W100°C. n COPYRIGHT: (C)1982,JPO&Japio
priorityDate 1981-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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