http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S57118579-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D331-02 |
| filingDate | 1981-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1abb4e25b62532fcdfaa461656ca695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59b72f1da74dc80480bf5c440b9dc994 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_156db00e2d809bd00983d9dfed3f70f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9df103f319686cb2ef4ebe21ccd9fcb7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58130fe647e27e142b22ad2c2d0e4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eeae1b777201c1ca98d195cb4e84ad1 |
| publicationDate | 1982-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S57118579-A |
| titleOfInvention | Leukotriene a analogous compound, its preparation and remedy for disease caused by leukotriene containing the same as active constituent |
| abstract | NEW MATERIAL:A compound of formulaI(R 1 is H or 1W5C alkyl; R 2 is 10W 14C saturated or unsaturated straight chain alkyl; X is O or S; m is 2, 3 of 4) and a nontoxic salt thereof. n EXAMPLE: 5,6-trans-Epoxy-7-trans-9-cis-eicosadienoic acid. n USE: A preventing agent and remedy for allergic bronchitis, pneumonia or shock and other diseases, having inhibitory activity against 5-lipoxygenase. n PROCESS: The triple bond in a compound of formula II as a starting substance is catalytically reduced to give a cis-double bond convert the hydroxymethyl group into an aldehyde and the oxo group into an OH group. The resultant compound is then epoxidized to afford a compound of formula III(R 11 is 1W5C alkyl), which is reacted with an alkali mtallic rhodanide in a solvent to give the compound of formulaI(X is S). The resultant compound is then saponified to give the aimed substance of formulaI(R 1 is H). n COPYRIGHT: (C)1982,JPO&Japio |
| priorityDate | 1981-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.