| abstract |
NEW MATERIAL:An N-(2-thiazolyl)carbamate derivative shown by the formulaI (R is H, lower alkyl, cycloalkyl, thienyl, furyl, pyridyl). n EXAMPLE: 2,2,2-Trichloroethyl N-[4-(4-pyridyl)thiazole-2-yl)carbamate. n USE: A drug effective for immune diseases such as rheumatoid arthrits, also useful for viral diseases or carcinostatic immunotherapy, having immune adjusting ability and antarthritic action. Having low toxicity. n PROCESS: For example, an aminothizole shown by the formula II is reacted with 2,2-chloroformic acid 2,2,2-tricyloroethyl ester in a solvent such as benzene, etc., to give a compound shown by the formulaI. n COPYRIGHT: (C)1982,JPO&Japio |