abstract |
PURPOSE: An antidiabetic agent, containing an aminobenzoic acid or a salt thereof as a principal constituent, and having a low toxicity and improved hypotensive action without side effects. n CONSTITUTION: An antidiabetic agent containing an aminobenzoic acid expressed by the formula (R 1 is arabinose, xylose, glucose, galactose or rhamnose residue) or a salt thereof, and particularly suitable for the oral administration. The agent is administrable for a long term due to the low toxicity and neither antimicrobial activity nor fear for the disturbance of intestinal lawn. There is no danger of teratogenicity, allergic reactions, etc. due to no influence on the mutagenicity, cellular and body fluid immunity. The daily dose per kg body weight preferably 1W250mg for the oral administration and 0.1W100mg for the parenteral administration in one W divided four fractions. n COPYRIGHT: (C)1982,JPO&Japio |