| abstract |
PURPOSE: A safe hypotensive agent, containing aminobenzoic acid-N-D-mannoside or a salt thereof, usable continuously for a long term, having a high medicinal suitability and improved hypotensive action without exhibiting the mutagenicity. n CONSTITUTION: A hypotensive agent containing a compound of formulaIor a salt thereof as an active constituent. The compound of formulaIis used in an amount of 0.001W100wt% as an active constituent in the dosage form of powder or granule. The compound may assume any oral or parenteral administration form in use as an antidiabetic agent. In use for men and animals, the agent is preferably administered orally. The oral administration includes the sublingual administration. The daily dose per kg body weight for men is preferably 1W 400mg for the oral administration and 0.1W100mg for the parenteral administration in one W divided four fractions. The compound of formula II is particularly useful. n COPYRIGHT: (C)1982,JPO&Japio |