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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C239-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-16
filingDate 1980-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cc2765de459931200b9868268298a6a
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publicationDate 1981-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S5699453-A
titleOfInvention Crystallizing method of citrulline
abstract PURPOSE: To obtain a granular citrulline anhydride crystal having improved storage stability, by inoculating a δ crystal of citrulline anhydride into a saturated or supersaturated solution of citrulline, and concentrating and crystallizing the citrulline anhydride under specific conditions. n CONSTITUTION: A saturated or supersaturated solution of citrulline (raw solution for crystallization) is inoculated with about 0.1W30%, based on the total crystallized amount, δ crystal of citrulline anhydride at 45°C or above. The solution is then concentrated and crystallized while maintaining the concentration of the citrulline in a metastable supersaturation region at 45°C or above to give a granular crystal of citrulline. As for the raw solution for crystallization, a crude crystal of citrulline dihydrate or a solution treated with an ion exchange resin is used. The method is suitable particularly for the final crystallization of the citrulline. n COPYRIGHT: (C)1981,JPO&Japio
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