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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C313-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-41
filingDate 1979-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fc684e1e0312d9ec5322bcc09edb743
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2bd384c300d333f153f9b58a34838fb
publicationDate 1981-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S5695162-A
titleOfInvention Novel synthesis of pantethine
abstract PURPOSE: To obtain pantethine useful as a drug in high yield and in high purity, by condensing panthothenic acid or its salt with cystanine or its salt in the presence of 2-mercaptobenzimidazole. n CONSTITUTION: Panthothenic acid or its salt (e.g., calcium panthothenate, sodium panthothenate, etc.) is reacted with cystamine or its salt (e.g., cystamine hydrochloride, cystamine sulfate, etc.) in the presence of 2-mercaptobenzimidazole using a carbodiimide (e.g., dicyclohexylcarbodiimide, etc.) as a condensation agent in a solvent, e.g., pyridine, dimethylformamide, etc. to give pantethine. 2-Mercatobenzimidazole contributes to the improvement of the yield specifically. n COPYRIGHT: (C)1981,JPO&Japio
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5846062-A
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