http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S568383-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7478ccf6996666c3d6ed739dc2d5ec7d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D475-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08H1-00 |
| filingDate | 1979-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23a46d62a498fda2480461c436ce1ff9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f68a5122fe7191defd19f30d8a229807 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee8c496442d4217705808f90a51448a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9973398abb6653ffc5b2cf1a59034ea4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f724712f907451ebe4d67d9a01b0081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9989e15c259fba2939e5d31e632af1d |
| publicationDate | 1981-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S568383-A |
| titleOfInvention | Pterin derivative and determination of pterin |
| abstract | NEW MATERIAL:The titled compound of formula I (Q is alkylene group which may be substituted by an alkyl or aralkyl group; R is OH, tyramine, etc.; R 6 and R 7 are H, alkyl groups, etc.). n EXAMPLE: 4-Amino-2-[(IS)-1-carboxyethylamino]-6-hydroxy-5-nitropyrimidine. n USE: A tracer for radioimmunoassay of pterin in the specimen, e.g. urine, or an antigen for producing the antibody. n PROCESS: A nitrosopyrimidine derivative of formula II is heated with an amino acid of formula III under refluxing to form a compound of formula IV, whose 5-nitro so group is reduced in the presence of a suitable catalst to give a 4,5-diamino derivative of formula V. The resulting compound of formula V is subjected to condensation and ring closure with diacetyl or glyoxal in a solvent under heating to afford a compound of formula VI, which is reacted with a chloroarbonic ester in the presence of a tertiary amine and then with tyramine etc. to give the compound of formula I. n COPYRIGHT: (C)1981,JPO&Japio |
| priorityDate | 1979-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.