http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5665895-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-57 |
filingDate | 1979-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cec93e37ebe416dd636834c067576a14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b13559d7efcfd4e3677ed78a00363682 |
publicationDate | 1981-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S5665895-A |
titleOfInvention | Novel 7alpha-methoxycephalosporin compound |
abstract | NEW MATERIAL:The titled compound of formula I [R is aryl, (aryl-substituted) lower alkyl, or halogen-substituted lower alkyl; A is H, (acetoxy)methyl, or heterocyclic thiomethyl], and its derivative at the carboxyl group. n EXAMPLE: 7α-Methoxy -7β- [ 2-( p-toluenesulfonyloxy )acetamido]cephalosporanic acid (salt). n USE: Intermediate of 7α-methoxycephalosporin compound which is an antimicrobial agent effective to resistant microbials. n PROCESS: For example, a compound of formula II or its derivative at the amino group or carboxyl group is made to react with a sulfonyloxyacetic acid of formula III or its reactive derivative at the carboxyl group, and the resulting compound of formula IV is treated with a halogenating agent in the pesence of an alkali metal salt of methanol (pref. lithium methoxide) and methanol to obtain the objective compound of formula I. n COPYRIGHT: (C)1981,JPO&Japio |
priorityDate | 1979-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.