http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5663992-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_204ea9f0f83d1c51a916e46a41a6a14a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-22 |
| filingDate | 1979-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92b5dbdbb2968008aeb158620c8ee760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cc8c532f23ec9a96265116bf431ba70 |
| publicationDate | 1981-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5663992-A |
| titleOfInvention | 3',4',4",6"-tetradeoxyamikacin and its preparation |
| abstract | NEW MATERIAL:3',4',4",6"-Tetradeoxyamikacin of formula I and its acid addition salt. n USE: An antimicrobial agent having lower toxicity to the hearing orgen as well as acute toxicity than amikacin used as a raw material. It is effective to a side variety of resistant microorganisms. n PROCESS: The compound of formula I is prepared by (1) introducing a protecting group to 3',4'-dioxyamikacin of formula II, (2) removing the 4" and 6"-protecting groups from the resulting compound of formula III [A is H; B is univalent NH 2 - protecting group, or A and B together form a bivalent NH 2 -protecting group; the group of formula IV (X, Y are H, alkyl, etc.) is bivalent OH-protecting group or cycloalkane; D is acyl-type OH-protecting group; E is D or H], to obtain the compound of formula V, (3) converting the 4"- and 6"-OH groups of the compound of formula V to sulfonic acid esters, (4) iodizing or brominating the product, (5) dehalogenating by catalytic redction, and if necessary, (6) eliminating the residual protecting groups from the resulting compound. n COPYRIGHT: (C)1981,JPO&Japio |
| priorityDate | 1979-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.