http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5659773-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47
filingDate 1979-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64bf4428d69a997e1caabf4a0f5289b1
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publicationDate 1981-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S5659773-A
titleOfInvention Preparation of benzo ij quinolidine-2-carboxylic derivative and its preparation
abstract NEW MATERIAL:Benzo[ij]quinolidine-2-carboxylic acid derivatives of formula I (R 1 is Br; R 2 is Cl, F) and their salts. n EXAMPLE: 9-Fluoro-8-bromo-5-methyl-6, 7-dihydro-1-oxo-1H, 5H-benzo[ ij ]quinolidine-2-carboxylic acid. n USE: Antibacterial and synthetic intermediate of compounds used as antibacterials: they have outstanding activity against gram-positive and -negative bacteria, especially being very effective on Streptococcus, Psedomonas and Enterobacter. They show antibacterial activity also against Escherichia coli, Staphylococcus, further Serratia and Klebsiella and low toxicity. n PREPARATION: A compound of formula II reacts with another compound of formula III (R 4 , R 5 are lower alkyl) to form a compound of formula IV, which is cyclized to give a compound of formula V. The product is hydrolyzed to give the compound of formula I. n COPYRIGHT: (C)1981,JPO&Japio
priorityDate 1979-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 21.