http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5655400-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630b360599ea5cf4b5bcbc0c6c0a3e2d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-0045 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 1979-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d9e40ae2de6784c1ce22ee8fdcc4a72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2e71b2ccb8fac6dbf0139ac76f1dc9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_932d251d76dba73f2f7d4d1810c7f646 |
| publicationDate | 1981-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5655400-A |
| titleOfInvention | Improved preparation process of 4,6-dien-3-one steroid |
| abstract | PURPOSE: To prepare the titled compound useful as an intermediate of active corpus luteum hormone, antiandrosterone diuretic, hypotensive agent, etc., economically, in an industrial scale, by the bromination and then dehydrobromination reaction of an enol ether of a specific steroid under specific conditions. n CONSTITUTION: An enol ether of a steroid wherein the 3, 4, 5, and 6-positions of the A- and B-rings are group of formula I (X 1 is H, methyl, F, Cl or Br; R 1 is 1W3C alkyl) is brominated with a halogenating agent capable of supplying positive bromine ions, in a water-containing organic solvent free of acetic acid and sodium acetate to obtain 6-bromosteroid of formula II, which is subjected to the debromination in a solvent containing DMF or N-methylpyrrolidone by reacting directly with lithium halide and an inorganic carbonate maintaining the water contact in the solvent to 1W9wt% to obtain the objective compound of formula III. n COPYRIGHT: (C)1981,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002241395-A |
| priorityDate | 1979-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.