http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5645482-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14b02369b953bf4ebd31190c8cb63473 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 |
| filingDate | 1979-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb57065da4e3cbc8c91f4306cc854d6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6c6271aa7a69f61a193ad6881902d28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba31b9bc677a6eb0cc50af98f3ce7bb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a4ec5b7df5d5cba3118bd737774a190 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_077d2abfaad9b26f42901cd1d602159a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c1e2ba5f4ca45e999cf599803e84766 |
| publicationDate | 1981-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5645482-A |
| titleOfInvention | 3-sulfonylrifamycin and its preparation |
| abstract | NEW MATERIAL:Compounds of formula I or II (X is acetyl, H; R is alkyl, phenyl, substituted phenyl). n EXAMPLE: 3-(Methylsulfonyl)rifamycin SV. n USE: Antibiotic. n PREPARATION: Rifamycin S of formula III or its 25-acetyl derivative in an inert solvent such as DMSO or DMF is combined with a citric acid buffer solution or diluted hydrochloric acid so that the solution becomes acidic. Then, sulfinic acid or its salt is made to react therewith to give 3-sulfonylrifamycin of formula I or its 25-deacetyl derivative. The reaction temperature is kept to room temperature to 30°C. The compound of formula I is treated with an oxidizing agent such as manganese dioxide to form 3-sulfonylrifamycin of formula II or its 25-deacetyl derivative. n COPYRIGHT: (C)1981,JPO&Japio |
| priorityDate | 1979-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.