http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5634633-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a09ca043d7e596facff1f44b746e2f4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 1979-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7903d3b6e95f35b2b3672f2be445a187 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38ba6321b467ba324c4d5978da3e181d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ae89a81f80c9660b9e95fa51d338e5d |
| publicationDate | 1981-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5634633-A |
| titleOfInvention | Preparation of s-sulfonated immunoglobulin rich in monomer |
| abstract | PURPOSE: To prepare the titled compound having lowered anticomplementary value and suppressed side effects, by adding a salt of a specific organic compound to a solution of S-slulfonated immunoglobulin containing agglutinated material. n CONSTITUTION: A solution of S-sulfonated immunoglobulin containing agglutinated material, is mixed with 10W600wt%, based on the S-sulfonated immunoglobulin, of a water-soluble salt of a nitrogen-containing organic base having a dissociation index (pKb) of ≥7, e.g. l-arginie hydrochloride, and D-glucosamine hydrochloride, to dissociated the agglutinated material into monomers and to obtain the objective S-sulfonated immunoglobulin rich in monomer. The addition of the water-soluble salt is effective to dissociate the agglutinated material rapidly into the monomers, and to reduce the anticomplimentary value for a long period. The lowering of the anticomplimentary value prevents the anaphylactic side effects accompanied with lowering of blood pressure, algor and pyrexia. n COPYRIGHT: (C)1981,JPO&Japio |
| priorityDate | 1979-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.