http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5632477-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5323fd442d8a622c3ea5a91d47113e52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31f26bd884587818b9d2579ce0c1f509 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-04 |
| filingDate | 1979-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90be3d2def15846f0bdb67168aa6141d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ee3d19bc0078ecf3814be19d36dc1e3 |
| publicationDate | 1981-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5632477-A |
| titleOfInvention | Preparation of 1- 5-oxohexyl -3,7-dimethylxanthine |
| abstract | PURPOSE: To obtain the titled compound useful as a remedy for circulatory disorder, in one stage, by reacting a 1-(3-substituted propyl)-3,7-dimethylxanthine with acethylacetone under specific conditions. n CONSTITUTION: A compound of formula II (X is halogen or organic sulfonyloxy) is reacted with acetylacetone of formula III in the presence of an alkali hydroxide in an alcoholic solvent to give the compound of formula I. In order to suppress side reactions, 2W10mol, preferably 3W5mol, the compound of formula III is used per one mole the compound of formula II. The use of an aprotic polar organic solvent, e.g. DMF or N-methylpyrrolidone, with the alcoholic solvent accelerates the reaction and increases the yield. n COPYRIGHT: (C)1981,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011028835-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5756481-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S58138294-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3199203-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013155465-A1 |
| priorityDate | 1979-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.