http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5630998-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_204ea9f0f83d1c51a916e46a41a6a14a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 1979-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cc8c532f23ec9a96265116bf431ba70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92b5dbdbb2968008aeb158620c8ee760 |
publicationDate | 1981-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S5630998-A |
titleOfInvention | 1-n-(l-4-amino-2-hydroxybutyryl)derivative of 6'-c-alkyl-3'-deoxykanamycin b or 6'-c-alkyl-3',4-dideoxykanamycin b |
abstract | NEW MATERIAL:The titled compound shown by the formula I (R is hydroxyl or H; one of R 1 and R 2 is H, and the other is 1W6C alkyl) and its acid addition salt. n EXAMPLE: 1-N-( L-4-Amino-2-hydroxybutyryl )-6'( R )-C-methyl-3'-deoxykanamycin B. n USE: An antibacterial agent effective against a resistant bacterium, sensitive bacterium, etc. n PROCESS: An amino group of a 6'-C-alkyl-3'-deoxykanamycin B or 6'-C-alkyl-3', 4'-dideoxykanamycin B shown by the formula II or their derivative wherein 4 amino groups except the amino group in the 1st position, and, if necessary, hydroxyl groups, are at least partially protected by protecting groups is acylated by L-4- amino-2-hydroxybutyric acid. The protecting groups of the reaction product are removed conventionally to give a compound shown by the formula I. n COPYRIGHT: (C)1981,JPO&Japio |
priorityDate | 1979-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.