http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S562974-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-16 |
| filingDate | 1979-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_271b978b5f3f418dc878b7beed189c53 |
| publicationDate | 1981-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S562974-A |
| titleOfInvention | 1-substituted benzodiazepine derivative, its salt, and its novel preparation |
| abstract | PURPOSE: To obtain the titled composition useful as a drug having sadative, muscle relaxant, and hypnotic action, etc. by reacting a 1-unsubstituted-1,4-benzodiazepine-2-one with a lower alkylvinylsulfone. n CONSTITUTION: A 1-unsubstituted-1,4-benzodiazepin-2-one, e.g., a bensodiazepine derivative shown by the formula I (R 1 is H, halogen, nitro, etc.; R 2 and R 3 are H, halogen, or lower alkyl) is reacted with a lower alkylvinysulfone shown by the formula II (R 4 is lower alkyl) in a solvent, e.g., methanol, preferably in the presence of a catalyst, e.g., sodium methylate at room temperatures or under heating to give a 1-(β-lower alkylsulfonylethyl)-1,4-benzodiazepin-2-one, e.g., a 1-substituted benzodiazepine derivative shown by the formula III. n COPYRIGHT: (C)1981,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4973315-A |
| priorityDate | 1979-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.