http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5615264-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_067cda10aaf6d4a5ca8180abe5a545c6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 |
| filingDate | 1979-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f01cfa7289bb968c35afd2dc09012ca1 |
| publicationDate | 1981-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5615264-A |
| titleOfInvention | Preparation of indole derivative |
| abstract | PURPOSE: To prepare the titled compound, easily economically, in high purity and yield, by reacting a stable and easily handleable nitrotoluene derivative with di(thio)acetal of N,N-di-substituted (thio)formanide, and reducing the reaction product. n CONSTITUTION: The indole derivative of formula I (R is alkyl) is prepared by reacting (A) a nitrotoluene derivative of formula II with (B) an acetal compound of formula III (R 1 , R 2 are alkyl, aralkyl, or aryl; Q is or S; R 1 may be H), e.g. dimethyl(thio)acetal of dimethylformamide, and reducing the reaction product by catalytic reduction, etc. The reaction is carried out pref. at about 50W200°C under atmospheric pressure. n USE: Remedy and preventive for arrhythmia, auricular fibrillation and coronary vessel diseases. n COPYRIGHT: (C)1981,JPO&Japio |
| priorityDate | 1979-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.