abstract |
NEW MATERIAL:N 1 -Cholesteryloxycarbonyl-5-fluorouracil. n USE: A carcinostatic agent. Having a small side effect and good absorption. n PROCESS: For example, 5-fluorouracil is reacted with chloroformic ester of cholesterol in the presence of a base, e.g., triethylamine, etc. in a solvent, e.g., DMF to give the titled compound. n COPYRIGHT: (C)1981,JPO&Japio |