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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
filingDate 1980-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c25440c1c5dd4b2cc880a922187f5f52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aef09cd6facbd064b64927cfd1025971
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publicationDate 1981-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S56147765-A
titleOfInvention Preparation of active vitamin d3
abstract PURPOSE: To obtain the titled compound useful as a calcium metabolic adjustor, by isomerizing a hydroxycholesta-5,7-diene protected by a lower alkoxy group thermally under irradiation of ultraviolet light. n CONSTITUTION: A hydroxycholesta-5,7-diene of formula I (R 1 and R 2 are lower alkoxycarbonyl R 3 and R 4 are H or lower alkoxycarbonyloxy) is isomerized thermally under irradiation of ultraviolet light to give a mixture of an active vitamin D 3 derivative of formula II in which the hydroxyl groups are protected with the unreacted hydroxycholesta-5, 7-diene of formula I. The unreacted compound of formula I and the compound of formula II are then separated from the resultant mixture, and the unreacted compound of formula I is circulated for reuse. The protecting groups in the compound of formula II are then removed to afford the titled compound of formula III (R 3 ' and R 4 ' are H or OH). n COPYRIGHT: (C)1981,JPO&Japio
priorityDate 1980-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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