http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S56135488-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5128cfc84a0fb189fceb3cd240c44493 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 |
filingDate | 1980-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db86e55564a7a83dc416272fe23f1d38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e54540470e27a6ccbb2e43ec51a814f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_398b0597e6a3aa14a2978b2fdbd9c585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c64c0970e75edd82df83d270adb6c17c |
publicationDate | 1981-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S56135488-A |
titleOfInvention | Novel preparative method of cephalosporanic acid derivative |
abstract | PURPOSE: A 7-aminocephalosporanic acid derivative is made to react with a novel active ester to safely produce the titled derivative used as an antibiotic agent against grampositive and -negative bacteria in high yield. n CONSTITUTION: The reaction between a 7-aminocephalosporanic acid derivative of formula I (R 1 is halogen, azide, benzimidazole) and 2-amino-1,3-thiazol-4-yl-acetic 1-dimethylaminoethyl-tetrazol-5-yl thiol ester is conducted, preferably at a molar ratio of 1:(1W2) in a solvent of DMF at 40W80°C to give the objective cephalosporanic acid derivative or its salt of formula III. The compound of formula II is novel and obtained, e.g., by reaction of 1-dimethylaminoethyl-tetrazole-5-thiol of formula IV with 2-amino-1,3-thiazol-4-ylacetic acid in a solvent at -50W+100°C. n COPYRIGHT: (C)1981,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107488185-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0320397-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6064986-A |
priorityDate | 1980-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.