http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S56131597-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate | 1981-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdeae387f15559f76e72be3a5a026705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf1c26d69ef14503a514eef041bb818e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7274f27d52fbca78779e985b4e65a064 |
| publicationDate | 1981-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S56131597-A |
| titleOfInvention | Preparation of n2-lower alkanoylphenyl-2,6- diaminoneburaline |
| abstract | NEW MATERIAL:A neburaline compound of formula I (Ph is lower alkanoylphenyl group). n EXAMPLE: N 2 -(3-Acetylphenyl)-2,6-diaminoneburaline. n USE: A coronary arterial vasodilator and a blood platelet agglutination inhibitor with little side effects and low toxicity and useful as a remedy for an ischemic heart diseases, e.g. coronary failure or angina pectoris. n PROCESS: A compound of formula II [R 1 , R 2 and R 3 are (protected) OH] obtained from 5-amino-1-β-D-ribofuranosylimidazole-4-carboxamide which is a fermentation product in a short step in high yield is reacted with a compound of formula III [X is (substituted) amino or lower alkylthio], and if necessary the protecting groups are removed to give the titled compound of formula I. The method has advantages that the aimed substance can be obtained in a short step in high yield under ordinary pressure without requiring a catalyst and easily separated with little by- products. n COPYRIGHT: (C)1981,JPO&Japio |
| priorityDate | 1980-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.