| abstract |
NEW MATERIAL:A 2-(3,4,5-trimethoxyphenyl)-4-methyl-5-acetylthiazole shown by the formula I. n USE: A drug for ulcer having antidigestive action. A hypotensive and a sedative. n PROCESS: A compound shown by the formula II is reacted with a compound shown by the formula III (X is halogen) under heating to give a compound shown by the formula I. Since the compound shown by the formula II is obtained by the reaction of a compound shown by the formula IV with diphosphorus pentasulfide, a mixture of diphosphorus pentasulfide and the compound shown by the formula IV instead of the compound shown by the formula II may be used in the reaction to give the desired compound. n COPYRIGHT: (C)1981,JPO&Japio |