| abstract |
PURPOSE: An immuno-chemotherapeutic, drug resistance preventing, carcinostatic agent containing a specific benzene derivative having a carbon-containing chain, as an effective component. n CONSTITUTION: A carcinostatic agent having remarkable immune-promoting and drug resistance preventing effects by itselt, is prepared by using a compound of formula (R 1 is H, OH, hydroxyalkoxy, phenoxy, alkyl, etc.; R 2 is H or OH; R 3 is H, OH, alkoxy, hydroxyalkyl, etc.; R 4 is H, OH, alkoxy, carboxyalkoxy, etc.; R 5 is H, OH, alkoxy, etc.; R 6 is H, OH, alkoxy, etc.) or its functional derivative (e.g. mandelic acid, 4-hydroxy-3-methoxymandelic acid, etc.), as an effective component. The agent exhibits an additive effect when used in combination with known carcinostatic agents, general antibiotics, and vaccines, and increases the antibacterial effects of these substances. n COPYRIGHT: (C)1981,JPO&Japio |