| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a09ca043d7e596facff1f44b746e2f4d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-831
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-83 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate |
1980-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12dc2aa1ee201882e1845d2fe6bdfbae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7903d3b6e95f35b2b3672f2be445a187
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e901fe6d06ef82f9ef63ab73fe6c5655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38ba6321b467ba324c4d5978da3e181d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0b0f4f6eeb44a3b4cc8bafb8eca55eb |
| publicationDate |
1981-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S56113713-A |
| titleOfInvention |
Preparation of immunoglobulin with high content of monomer |
| abstract |
PURPOSE: To obtain the titled compound useful for preventing and remedying various infectious diseases, by fractionating immunoglobulin-containing material in the presence of a specific basic compound with preventing the formation of aggregate with side effects. n CONSTITUTION: Immunoglobulin is collected from an immunoglobulin-containing material (e.g., serum or plasma) by fractionation. In the operation, a water-soluble solution of a basic nitrogen-containing organic compound (e.g., arginine) having a dissociation constant pKb not more than 7 is added to the immunoglobulin-containing material during the process of fractionation (especially, initial process), to give immunoglobulin with high content of monomer. The addition of the basic compound prevents the immunoglobulin monomer occurring during fractionation process from agglomerating into a dimer or polymer. These agglomerates activate a complement component, consequently various side effects are brought about. n COPYRIGHT: (C)1981,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009046494-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08175908-A |
| priorityDate |
1980-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |