http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5610151-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_067cda10aaf6d4a5ca8180abe5a545c6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate | 1979-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f01cfa7289bb968c35afd2dc09012ca1 |
| publicationDate | 1981-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5610151-A |
| titleOfInvention | Preparation of nitrotoluene derivative |
| abstract | PURPOSE: To obtain advantegeously the titled compound useful for remedying or preventing arrhythmia and diseases of atrial fibrillation and coronaria, having β-adrenergic neuronal blocking action, by hydrolyzing oxazolidinone. n CONSTITUTION: A compound shown by the formula I(R is alkyl) is hydrolyzed in the presence of an acid (e. g., hydrochloyic acid, etc.) or a base (e. g. NaOH, etc.) at 20°C to the boiling point of the reaction mixture to give a nitrotoluene dirivative shown by the formula II. The conpound shown by the formula I as a starting material is obtained by reacting a compound shown by the formula III [Z is a group shown by the formula IV or -CH(OH)-CH 2 X (X is OH or halogen)] with a urea derivative shown by the formula V (R 1 is amino, alkoxy, or halogen; R 2 is H or alkyl) or an alkyl ester or a halogenide of a N-alkylcarbamic acid shown by the formula V (R 1 is amino, alkoxy, or halogen; R 2 is H or alkyl), or by alkylation in case that R 2 is H. n COPYRIGHT: (C)1981,JPO&Japio |
| priorityDate | 1979-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.