http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5610149-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_067cda10aaf6d4a5ca8180abe5a545c6 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-34 |
filingDate | 1979-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f01cfa7289bb968c35afd2dc09012ca1 |
publicationDate | 1981-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S5610149-A |
titleOfInvention | Preparation of nitrotoluene derivative |
abstract | PURPOSE: To obtain advantageously the titled compound useful as drugs, their intermediates, especially as a β-adrenergic neuronal blocking agent, by reacting a 2- methyl-3-nitrophenol with a specific secondary amine. n CONSTITUTION: A compound shown by the formula I (Y is H or alkali metal) is reacted with a compound shown by the formula II [R is alkyl; Z is epoxy or a group shown by the formula III (X is halogen)] to give a nitrotoluene derivative shown by the formula IV. The reaction is carried out in the presence or sbsence of a solvent, e. g., benzene, toluene, etc. preferably at 30W200°C. When a compound wherein Z is the group shown by the formula III is used, a base, e. g., NaOH, KOH, etc. is perferably present in the reaction. n COPYRIGHT: (C)1981,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62174868-U http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S58113472-U |
priorityDate | 1979-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.