http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5564541-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-587 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 |
| filingDate | 1978-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59b72f1da74dc80480bf5c440b9dc994 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_156db00e2d809bd00983d9dfed3f70f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eeae1b777201c1ca98d195cb4e84ad1 |
| publicationDate | 1980-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5564541-A |
| titleOfInvention | Intermediate of prostaglandin i2 analog and its preparation |
| abstract | NEW MATERIAL:Intermadiates of prostaglandin I 2 analogs of formula I [either R 1 or R 2 is H and the other is -(CH 2 ) 4 -COOR 6 (R 6 is alkyl), R 1 and R 2 may incorporate to form oxo, =CH-(CH 2 ) 3 -COOR 6 , R 3 is benzyloxymethyl, hudroxymethyl, formyl, etc.; R 4 is H, group protecting hydroxyl; R 5 is H, Br where in this case R 1 and R 2 form oxo and R 3 is benzyloxymethyl)]. n EXAMPLE: 6-sym-Benzyloxymethyl-7-anti-hydroxy-8-sym-bromo-cis-bicyclo[3,3,0] octane-3-one. n USE: Intermediates of synthetic prostaglandin I 2 analogs that has the same physiological activities as natural PGI 2 useful as arteriosclerosis, heart failure, and thrombosis. n PREPARATION: For example, a compound of formula II and a sodium derivative of dialkylphosphonate of formula III (R 10 is alkyl) are subjected to Witting reaction to produce trans-enone derivative of formula III. n COPYRIGHT: (C)1980,JPO&Japio |
| priorityDate | 1978-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.