http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5562067-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-62 |
filingDate | 1978-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa2e7bacbde34f538d3e368c97b93efb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b011ef87de590b691fd76b5ea3aa91e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fc415ca6eaf3690db5eb0fa71eb9856 |
publicationDate | 1980-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S5562067-A |
titleOfInvention | Production of imidazoles |
abstract | PURPOSE: In the presence of a trivalent phosphorous oxyacid ester, the reaction of a triphenylmethanol that is chemically stable and less reactive with an imidazole unsubstituted in the 1-position is effected at not higher temperatures to produce title compound that has antifungal activity in high yield. n CONSTITUTION: The reaction of a triphenylmethanol in which the phenyl groups are substituted or unsubstituted with an imidazole unsubstituted in the 1-position in a solvent as pyridine, benzene, etc., is effected in the presence of an oxyacid ester of 3-valent phosphorous at 0°C - the boiling point of the solvent, preferably room temperature - the boiling point of the solvent to produce 1-triphenylmethylimidazole. The oxyacid ester of 3-valent phosphorous is, e.g., triphenyl phosphite, diphenyl hydrogen phosphite or dimethyl hydrogen phosphite and the amount used is 0.5W3.0 moles based on the imidazole. The amount of the imidazole used is the equimolar or a litle excess based on the triphenylmethanol. n COPYRIGHT: (C)1980,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5562068-A |
priorityDate | 1978-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.