http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5545661-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47ec6de4e21e1b33a1f9946bbbcbd341 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-04 |
| filingDate | 1978-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cfd619ec31c831584133761de718b4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11687989a6fa03c7b15875598dbc813f |
| publicationDate | 1980-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5545661-A |
| titleOfInvention | Production of 1-(5'-oxohexyl)-3,7-dimethylxanthine |
| abstract | PURPOSE: The addition of water to novel 1-(5-hexynyl)-3,7-methylxanthine gives readily title compound useful as vasodilator with remarkable activity in high yield and purity. n CONSTITUTION: The hydration of novel 1-(5-hexynyl)-3,7-dimethylxanthine of formula I is effected in an appropriate solvent as aqueous acetic acid in the presence of a salt of mercuric, silver, cadmium or zinc, such as mercuric sulfate, silver phosphate, cadmium sulfate or zinc cdhloride, and a mineral acid as sulfuric acid with heating preferably above 50°C to form 1-(5-oxohexyl)-3,7-dimethylxanthine of formula II. The novel compound of formula I is obtained by reaction between a compound of formula III (X is halogen) and another compound of formula IV(Me is alkali metal) in a inert solvent preferably under reflux. n COPYRIGHT: (C)1980,JPO&Japio |
| priorityDate | 1978-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.