| abstract |
PURPOSE: To prepare the title compound useful as an intermeidate of antibiotic agent, by reducing a 4-dihydrocarbostyril derivative which is a known or an easily synthesizable compound. n CONSTITUTION: A benzo-hetero-compound of formulaII(R 1 is H, OH, amino, halogen, alkoxy, alkyl, alkanesulfonyloxy or allenesulfonyloxy; R 2 is H, halogen, alkoxy, alkyl, or phenylalkoxy; R 3 is H, halogen or alkoxy; l is 1W3), e.g. 5- methanesulfonyl-oxy-1,2,3,4-tetrahydroquinoline, is prepared by reducing a 3,4- dihydrocarbostyril derivative of formulaI, e.g. 5-methanesulfonyloxy-3,4-dihydrocarbostyril, preferably with a hydrogenating agent such as sodium borohydride. n COPYRIGHT: (C)1980,JPO&Japio |