http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5535024-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9575aa9deffac891c58962bae1ee889 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-22 |
| filingDate | 1978-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6bfa51580e15ef773654068b637bffa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360d1e0164faf3dfecf053ae62a589e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c9d13cb5276d3e6d871ecb8f4cd9966 |
| publicationDate | 1980-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5535024-A |
| titleOfInvention | Novel method of production of 3',4'-dideoxy-6'-n-methylkanamycin b |
| abstract | PURPOSE: 3',4'-Dideoxykanamycin B is condensed with triethyl orthoformate, the product is reduced with sodium borohydride or lithium borohydride, thus producing title compound being effective against various kinds of bacteria and resistant bacteria in high yield. n CONSTITUTION: Triethyl orthoformate is condensed on the amino group in 6' position in the compound of formula I and the product is reduced with sodium or lithium borohydride to produce the objective compound of formula II. The molar ratio of the triethyl orthoformate used to the compound of formula I is 8W80. Preferably the compound whose four amino groups are protected in 1, 3, 2', and 3" positions is employed in the reaction and the yield will be better. n USE: It also can be used as a starting material for more effective 1-N-(α-hydroxy -ω-aminoacyl)-6'-N-methyl-3',4'-dideoxykanamycin B. n COPYRIGHT: (C)1980,JPO&Japio |
| priorityDate | 1978-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.