| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
| filingDate |
1978-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d2aa62a61557dcc28e12b96f98d63c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8d115a2915edab95a941d1f6b9b90d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95de81087ecaa9d633d9c8a5a08c5c3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d603a9e08370817c4bd59845c3ed562 |
| publicationDate |
1980-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S5528914-A |
| titleOfInvention |
Preparation of optically active benzyl alcohol derivative |
| abstract |
NEW MATERIAL:Optically active α-[(α-methyl-3,4-dimethoxyphenethyl-amino) methyl]-2-hydroxybenzyl alcohol of formula I. n USE: Medicines having improved hypoglycemic action. n PROCESS: Dl-α-[(α-(methyl-3,4-dimethoxyphenethylamino)methyl]-2-benzyloxybenzyl alcohol of formula II is optically resolved to give optically active α-[(α- methyl-3,4-dimethoxyphenethylamino)-methyl]-2-penzyloxybenzyl alcohol, which is then catalytically reduced to form the objective compound of formula I. A diastereomer having a melting point of 104W105°C is preferred as the dl-isomer raw material. Diastereoisomer salts may be resolved by using an optically active N- acetyl-phenylalanineas an optical resolving agent. n COPYRIGHT: (C)1980,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0558824-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5412119-A |
| priorityDate |
1978-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |