http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5527111-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 |
| filingDate | 1978-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d5974dae9b0de9fee681f0aa4d5b923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b13559d7efcfd4e3677ed78a00363682 |
| publicationDate | 1980-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5527111-A |
| titleOfInvention | Preparation of cephapirin |
| abstract | PURPOSE: To prepare the high-quality title compound, easily in high yield, by reacting a compound obtained from sulfonylglycolic acid and 7-aminocephalosporanic acid, with 4-mercaptopyridine in a short time. n CONSTITUTION: Sulfonylglycolic acid of formula I (R is aryl or alkyl) or its reactive derivative in the carboxyl group, e.g. an acid halide, an acid azide, etc., and 7-aminocephalosporanic acid or its salt are reacted together. Subsequently, the obtained compound of formula II is reacted, with or without isolation, with 4- mercaptopyridine or its salt in mercapto group, in a solvent, preferably in the presence of an organic base. 7-[2-(4-Pyridylthio)acetoamide]cephalosporanic acid (=cephapirin) or non-toxic salts are obtained the yield of as high as 80W90%. n COPYRIGHT: (C)1980,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104211719-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104211718-A |
| priorityDate | 1978-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.