http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S552614-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d6daf2f7c988edb05837e47b1f88d91 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-00 |
| filingDate | 1978-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0ac93317be665fd2299894c3981af5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30ecc9fb0fd0a9a7e4b393269bd5814e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95b718b9ba3819e3bf7ee0fb56332006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca074ca34de46f0ae6785e210d6ccc24 |
| publicationDate | 1980-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S552614-A |
| titleOfInvention | Preparation of 2-artl alkane acid |
| abstract | PURPOSE: To obtain a 2-aryl alkane acid for use as antiphlogistic analgestic anodyne in high yield in a few steps, by using easily obtainable novel starting materials or intermediate product and reagents which are reacted under readily adjustable reaction condition.s n CONSTITUTION: 3-bromobenzophenone is reacted with ethylene glycol to prepare an acetal type bromo compound shown by the formula I, which is converted into Grignard reagent by metallic magnesium. This reagent is reacted with acetyl chloride or acetic anhydride in the presence of copper chloride to give a compound shown by the formula II, which is reacted with trimethylsulfonium methylsulfate and sodium methoxide to give an oxirane derivative shown by the formula III. The derivative undergos ring opening conversion reaction to prepare an aldehyde compound shown by the formula IV, which is oxidized under an acidic condition to give the desired compound shown by the formula V. The compounds shown by the formula IWV are new materials. n COPYRIGHT: (C)1980,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0529444-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0529444-A3 |
| priorityDate | 1978-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.