http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5522629-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00
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filingDate 1978-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc2947dba1f3ddfbe086215dca3ffa81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5884d2f13bf6e66606dbe752e3f5a96
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publicationDate 1980-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S5522629-A
titleOfInvention Preparation of 2(2,6-dichloroanilino)phenyl acetic acid
abstract PURPOSE: To prepare the title compound useful as an antiphlogistic, analgesic, and antipyretic in a simple process in high yield, by treating an alkali salt of 2-(2,6- dichloroanilino)-phenylpyruric acid with a mineral acid. n CONSTITUTION: A novel compound of formulaII: (R is lower alkyl, preferably methyl or ethyl group) is hydrolyzed in an alcoholic alkali hydroxide, preferably KOH or NaOH, to give a compound of formulaI: (M is alkali metal, preferably K or Na), which is treated with one or more types of mineral acids, preferably hydrochloric, sulfuric, or nitric acid, to form the desired 2-(2,6-dichloroanilino)- phenylacetic acid of formulaIII. The compound of formulaII can be readily obtained by reacting 2-(2,6-dichloroanilino)-benzaldehyde with a compound of formulaIV to form a compound of formulaV, which is oxidized. n COPYRIGHT: (C)1980,JPO&Japio
priorityDate 1978-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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