http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5522629-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc612b218d127b7f2e37c0a912cdead5 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-42 |
filingDate | 1978-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc2947dba1f3ddfbe086215dca3ffa81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5884d2f13bf6e66606dbe752e3f5a96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c0271cf9a60a9d40721dfaa664a813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33d0fef67476d557444d4e304b26978b |
publicationDate | 1980-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S5522629-A |
titleOfInvention | Preparation of 2(2,6-dichloroanilino)phenyl acetic acid |
abstract | PURPOSE: To prepare the title compound useful as an antiphlogistic, analgesic, and antipyretic in a simple process in high yield, by treating an alkali salt of 2-(2,6- dichloroanilino)-phenylpyruric acid with a mineral acid. n CONSTITUTION: A novel compound of formulaII: (R is lower alkyl, preferably methyl or ethyl group) is hydrolyzed in an alcoholic alkali hydroxide, preferably KOH or NaOH, to give a compound of formulaI: (M is alkali metal, preferably K or Na), which is treated with one or more types of mineral acids, preferably hydrochloric, sulfuric, or nitric acid, to form the desired 2-(2,6-dichloroanilino)- phenylacetic acid of formulaIII. The compound of formulaII can be readily obtained by reacting 2-(2,6-dichloroanilino)-benzaldehyde with a compound of formulaIV to form a compound of formulaV, which is oxidized. n COPYRIGHT: (C)1980,JPO&Japio |
priorityDate | 1978-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.