http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S55151582-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 |
| filingDate | 1979-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8be4d680d9d2735dc1c9be2a2ff834c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64bf4428d69a997e1caabf4a0f5289b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79482cdbb998e5892c120632db5cf851 |
| publicationDate | 1980-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S55151582-A |
| titleOfInvention | Preparation of piperazinyl benzheterocyclic carboxylic acid ddrivative |
| abstract | NEW MATERIAL:A piperazinylbenzheterocyclic carboxylic acid derivative shown by the formula I (R<1> is H or lower alkyl; R<2> is H, lower alkyl, benzoyl, etc.; R<3> is H or halogen; n is 1 or 2) and its salt. EXAMPLE:8-( 1-Piperazinyl )-5-methyl-6,7-dihydro-1-oxo-1H,5H-benz[ ij ]quinolizine-2-carboxylic acid. USE:Antibacterial agents. Having an activity against a Gram-positive and a Gram- negative bacteria, especially against bacteria of the genus Streptococcus, Pseudomonas, etc. PROCESS:A novel compound shown by the formula II (R<4> and R<5> are H or lower alkyl) is reacted with a tertiary nitrogen atom-containing aromatic heterocyclic compound, e.g., pyridine, picoline, etc. or a trialkylamine, e.g., trimethyl-amine and an anion donor compound, e.g., chlorine, sulfuric acid, etc. to give a compound shown by the formula III (Y<+> is trialkyl ammonium, etc.; Z<-> is an anion), which is hydrolyzed to prepare a compound shown by the formula I. |
| priorityDate | 1979-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.