http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S55143988-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9a4924d5a8264ec54b1c42580d1d539 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-36 |
| filingDate | 1979-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a76786ab71848455d489a6fd7555dd30 |
| publicationDate | 1980-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S55143988-A |
| titleOfInvention | Preparation of thienodiazepin-2-one derivative containing novel diamine derivative and novel diazepin derivative |
| abstract | PURPOSE: To prepare the title compound having tranquillizing activity, etc., economically, in high yield, from N-thiophene diamine through a novel diamine derivative and a 2-halogenomethyl-thienoazepin derivative. n CONSTITUTION: An N-thiophene diamine of formula I (R 1 , 2 are H, alkyl, halogen, etc.; R 3 is H, alkyl, lower alkoxy, etc.) is reacted with a compound of formula II (R 4 is H, halogen, NO 2 , etc.; when the bond between C and Z is double bond, Z is NH and X is lower alkoxyl, or Z is O and X is halogen, etc., and when the bond is triple bond, Z is N) to afford a diamine derivative of formula III (Y is NH or O), which is subjected to intramolecular cyclization to obtain a compound of formula IV (X 1 is Cl or Br). The substitution group X 1 of the compound IV is converted to various groups by conventional method to obtain novel thienodiazepin derivatives of formula V. The objective compound of formula VI can be prepared by treating the compound V with a proper oxidizing agent in the presence of an inert solvent. n COPYRIGHT: (C)1980,JPO&Japio |
| priorityDate | 1979-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.