http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S55139362-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5152bcb05bbc271001c0c3b31e8cc3c1 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18 |
filingDate | 1979-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9923149501c73db182080462ec86aabe |
publicationDate | 1980-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S55139362-A |
titleOfInvention | Preparation of aporphine-type compound |
abstract | PURPOSE: To prepare aporphine-type compounds, some of which have pharmaceutical activity, by the oxidative cyclization of N-oxides obtained from isoquinoline- form compound. n CONSTITUTION: An aporphine-type compound of formula II (e.g. corytuberine) is prepared by the oxidative cyclization (i.e. phenoloxidation) of an N-oxide of formula I (R is lower alkyl), e.g. reticulin N-oxide, in an alcoholic solvent such as methanol, ethanol, etc., in the presence of a catalyst such as cuprous chloride. The N-oxide of formula I can be prepared, e.g. by oxidizing an isoquinoline-form compound of formula III with an oxidizing agent such as H 2 O 2 , m-chloro-perbenzoic acid, etc. n COPYRIGHT: (C)1980,JPO&Japio |
priorityDate | 1979-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.