http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S55136299-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 |
| filingDate | 1979-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf1c26d69ef14503a514eef041bb818e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_797a0b1d94cd6df5a94322f9f333c6d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7274f27d52fbca78779e985b4e65a064 |
| publicationDate | 1980-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S55136299-A |
| titleOfInvention | Preparation of n2-substituted 2,6-diaminonebularine |
| abstract | PURPOSE: To obtain the title compound useful as coronary vasodilators and platelet aggregation inhibitors in a few steps industrially advantageously, by reacting a specific carboximidate with a phenylcyanamide. n CONSTITUTION: 5-Amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide is reacted with a reactive derivative of a carboxylic acid to protect the hydroxyl group, and alkylated to form a compound of formula I (R 2 WR 4 are hydroxyl groups which may be protected). The resulting compound is then reacted with a compound of the formula R-NH-Q [R is (substituted)phenyl group; Q is nitrile or formula II [X is (substituted) amino group, etc.]] to form the objective compound of formula III. Among the compounds of formula I, 5-amino-1-(2,3,5-tri-O-propionyl-β-D-ribofuranosyl)imidazole-4-carboxamide wherein the hydroxyl group is protected is a novel compound. n COPYRIGHT: (C)1980,JPO&Japio |
| priorityDate | 1979-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.