http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5511586-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_831bc88937acff5fab9c75c67882eca2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-234 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 |
| filingDate | 1979-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94a96391520648d3799ff0c12228254c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb042724dd8fcee7b7df29d123eb89ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b513caca01745f2f51fdaf2626d2aac6 |
| publicationDate | 1980-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5511586-A |
| titleOfInvention | 1-n-(omega-amino-alpha-hydroxyalkanoyl) derivative of 4'-deoxy-6'-n- methylkanamycin a |
| abstract | NEW MATERIAL:Title compounds of formula I (n is 0W2). n USE: Antibiotic for infection by gram-positive and -negative bacteria. n PREPARATION: 1,3-Ureido-kanamycin of formula II is carbobenzyloxylated and further acetylate by using acetic anhydride and pyridine. The catalystic hydrogenation is effected to form 4'-hydroxy derivative of formula III with free hydroxyl group in the 4'-position. Subsequently, the mesilation and thioacetylation, then hydrolysis are conducted to form 4'-dioxykanamycin-urea. The carbobenzyloxylation is effected to form the 3"-N-acetyl derivative, which is hydrolyzed to the 6'-NH 2 derivative. Further, benzylation, methylation are effected and the product is heated with hydrazine to make 6'-N-benzyl-6'-N-methyl-4'-deoxykanamycin, which is acylated and hydrogenated to give the objective compound of formula I (n is 1). n COPYRIGHT: (C)1980,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0252854-U http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S60102350-A |
| priorityDate | 1978-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.