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filingDate 1979-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e25894e8f6460c5b6d88db48b924de32
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publicationDate 1980-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S55111457-A
titleOfInvention Novel amino-alcohol derivative and its pharmacologically acceptable salt
abstract NEW MATERIAL:Amino-alcohol derivatives of formulas I-A and I-B, and their pharmacologically acceptable salts. n EXAMPLE: 1-(4-Isopropylsulfinylphenyl)-2-n-octylaminopropanol. n USE: Medicines having vosodilator, blood phatelet antiagglutinating, lipid metabolism improving, and cerebral metabolism improving actions, useful for preventing and treating cerebral circulation disturbance, heart diseases, e.g. ischemic diseases, or various diseases from peripheral circulation disturbance. n PROCESS: An amino-alcohol (A) of formula II is oxidized with preferably 1W5 equivalents of an oxidizing agent, e.g. hydrogen peroxide, peracetic acid, or potassium permanganate, in a solvent, e.g. water, acetone, or dichloromethane, in an amount of 5W100 times that of A at -20W100°C for 30minW7hr to give the compounds of formulas I-A and I-B stepwise. n COPYRIGHT: (C)1980,JPO&Japio
priorityDate 1979-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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